Use the Axii Sign to force one opponent to kill another. Do this 20 times.

Kill 50 opponents using the environment (e.g. swamp gas, insects or objects).

Complete the subplot involving Keira Metz.

Collect the formulae for 6 different bomb types.

Kill 5 foes in a fight without taking damage (except for Toxicity) and without using the Quen Sign.

Kill 3 opponents in one fight using 3 different methods (swords, bombs, crossbow, Signs, etc.).

Learn 12 potion formulae.

Have all possible Place of Power bonuses active at the same time.

Defeat an opponent in a fistfight without taking any damage.

Attack, counter, cast a Sign and throw a bomb (in any order) in under 4 seconds.

ME3: Acquire all trophies

Complete all three games in Mass Effect Legendary Edition on Insanity without changing difficulty