Researched a Splicer with the Research Camera.

Spent 2000 dollars at Vending Machines.

Defended yourself against the Big Sister without dying.

Paid your respects to the founder of Rapture.

Acquire all upgrades for all weapons

The player has completed the game on the Hard difficulty setting

The player has defeated Atlas

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

Fully upgrade five weapons

The player has broken Fontaine's mind control

Fully upgrade four weapons

The player has entered Sander Cohen's personal quarters

The player has defeated Andrew Ryan