Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

The player has broken Fontaine's mind control

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has successfully invented all possible ammo types

The player has completed Sander Cohen's great masterpiece

The player has successfully hacked a safe

The player has successfully invented at least one item

The player has defeated Peach Wilkins

The player has taken at least one Research Photo of a Splicer

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully hacked a vending machine

Make Eve fall in love with you.