Collect all trophies

Find all training manuals

Break into every locked door using shivs

Engage in all optional conversations

While in stealth, turn off the spotlight generator in Pittsburgh

Open all safes

Use bricks or bottles to lure an infected into attacking a human

Defeat Black Fang without getting hit

Win the brick throwing contest

Find all workbenches

Upgrade and then break one of every melee weapon

Fully upgrade a weapon

Craft every item