Acquire all upgrades for all weapons

Charged up the Ferris Wheel 9 different times in “A Shocking Turn of Events”

Rescued the Little Sister in “A Shocking Turn of Events”

Rescued the Little Sister in “The ‘I’ in Team” without destroying any Machine Gun Turrets

Rescued the Little Sister in “The ‘I’ in Team”

Complete the game on Survivor difficulty without using a Vita-chamber

The player has completed the game without harvesting any Little Sisters

The player has defeated Atlas

The player has become a Big Daddy

The player has either Harvested or Rescued every possible Little Sister

The player has broken Fontaine's mind control

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

Fully research the Little Sister