The player has defeated Andrew Ryan

The player has purchased every slot in one of the Plasmid or Tonic tracks

The player has completed Sander Cohen's great masterpiece

The player has fully upgraded two weapons

Hit the jackpot at a slot machine

The player has successfully invented at least one item

The player has fully upgraded one weapon

The player has acquired at least one weapon upgrade

The player has fully researched the Leadhead Splicer

The player has taken at least one Research Photo of a Splicer

The player has purchased one slot in any Plasmid or Tonic track

The player has successfully completed 50 hacks

The player has successfully hacked a security camera