Researched a Splicer with the Research Camera.

Defended yourself against the Big Sister without dying.

Hacked one of each kind of machine.

Adopted a new Little Sister for the very first time.

Defended yourself against Lamb's Assault in the train station.

Found your way back into the ruins of Rapture.

Complete the game on Survivor difficulty without using a Vita-chamber

Complete the game on Hard difficulty without using a Vita-Chamber.

The player has completed the game without harvesting any Little Sisters

The player has become a Big Daddy

Acquire all upgrades for all weapons

Fully upgrade five weapons