Defeated 3 Big Daddies without dying during the fight.

Got through a Gather with no damage and no one getting to the Little Sister.

Beat the Last Chapter Without Dying on Normal Difficulty or Harder

Killed 30 enemies using only Traps.

Complete the game on Survivor difficulty without using a Vita-chamber

The player has completed the game on the Hard difficulty setting

The player has completed the game without harvesting any Little Sisters

Find every audio diary

Acquire all upgrades for all weapons

Collect or Invent 58 Tonics in the Physical, Engineering and Combat tracks

Fully research the Rosie

Fully upgrade four weapons